Repeat lactate level predicts mortality better than rate of clearance

More evidence that cystatin C predicts mortality better than creatinine.

podocin facilitates nephrin signaling. J Biol Chem 276: 41543–41546, 2001 7. Huber TB, Simons M, Hartleben B, Sernetz L, Schmidts M, Gundlach E, Saleem MA, Walz G, Benzing T: Molecular basis of the functional podocin-nephrin complex: Mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains. Hum Mol Genet 12: 3397–3405, 2003 8. Huber TB, Schermer B, Muller RU, Hohne M, Ba...

"Lactate Shift," Rather Than "Lactate Clearance," for Serial Blood Lactate Monitoring?

Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone.

In this study, we investigated the prognostic value of serum sodium and hyponatremia (< or =130 mEq/L) in 262 cirrhotic patients consecutively listed, 19 of which died (7%), 175 survived (67%), and 68 underwent liver transplantation (26%) during 3 months of follow-up. Hyponatremia was present in 63% of patients who died, compared to 13% of those who survived (P < .001), whereas the proportion w...

A retrospective analysis of geriatric trauma patients: venous lactate is a better predictor of mortality than traditional vital signs

BACKGROUND Traditional vital signs (TVS), including systolic blood pressure (SBP), heart rate (HR) and their composite, the shock index, may be poor prognostic indicators in geriatric trauma patients. The purpose of this study is to determine whether lactate predicts mortality better than TVS. METHODS We studied a large cohort of trauma patients age ≥ 65 years admitted to a level 1 trauma cen...

Relatedness predicts phenotypic plasticity in plants better than weediness

Background: Weedy non-native species have long been predicted to be more phenotypically plastic than native species. Question: Are weedy non-native species more plastic than natives? Organisms: Fourteen perennial plant species: Acer platanoides, Acer saccharum, Bromus inermis, Bromus latiglumis, Celastrus orbiculatus, Celastrus scandens, Elymus repens, Elymus trachycaulus, Plantago major, Plant...